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1. Breast cancer – most common. Frequently involves spine, pelvis, ribs 2. Prostate cancer – classically causes osteoblastic (sclerotic) lesions 3. Lung cancer – often aggressive bone involvement 4. Kidney cancer – frequently lytic, higher fracture risk 5. Multiple myeloma- frequent lytic lesions. Bone pain, fractures, hypercalcemia are common | Blooddocdad
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