Antimicrobial resistance (AMR) occurs when germs like bacteria and fungi develop the ability to defeat the drugs meant to kill them. AMR is a 'One Health' issue, affecting humans, animals, plants, and the environment. Why it matters: We rely on antimicrobials to save lives, support health systems, protect food security, and safeguard livelihoods. AMR is already causing millions of deaths and massive economic losses, with the poorest communities most at risk. By 2050, unchecked AMR could push 28