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  1. SUBSTANCE Definition & Meaning - Merriam-Webster

    Jan 3, 2015 · The meaning of SUBSTANCE is essential nature : essence. How to use substance in a sentence.

  2. SUBSTANCE Definition & Meaning | Dictionary.com

    SUBSTANCE definition: that of which a thing consists; physical matter or material. See examples of substance used in a sentence.

  3. SUBSTANCE | English meaning - Cambridge Dictionary

    An ecosystem is a system controlled by the flow of energy, and substances such as water, carbon and phosphorus, exchanged among living things.

  4. substance noun - Definition, pictures, pronunciation and usage notes ...

    Definition of substance noun in Oxford Advanced Learner's Dictionary. Meaning, pronunciation, picture, example sentences, grammar, usage notes, synonyms and more.

  5. Substance - Definition, Meaning & Synonyms | Vocabulary.com

    Any material that possesses physical properties is called a substance. The word also refers to the gist or main idea of something. If you remember the main point of a lesson, you've got the substance.

  6. Substances - definition of Substances by The Free Dictionary

    Define Substances. Substances synonyms, Substances pronunciation, Substances translation, English dictionary definition of Substances. n. 1. a. That which has mass and occupies space; matter. b. A …

  7. Substance Definition & Meaning | Britannica Dictionary

    The pancreas secretes a substance called insulin. The floor was covered with a white, powdery substance that turned out to be flour. He had a history of substance abuse. When has he ever said …

  8. SUBSTANCE | definition in the Cambridge English Dictionary

    All athletes are tested for illegal substances. This substance is so radioactive that it glows in the dark. This substance stretches to any shape you want. Rubber is a flexible substance. Two days after he'd …

  9. Alcohol, Marijuana, CBD, Vaping, and Opioids - SAMHSA

    Sep 19, 2025 · The use and misuse of alcohol, tobacco, illicit drugs, and prescription medications affect the health and well-being of millions of Americans.

  10. Substance (chemistry) - Wikipedia

    Some chemical substances can be combined or converted into new substances by means of chemical reactions. Chemicals that do not possess this ability are said to be inert. Pure water is an example of …