A bumper rally in European stocks appears to be slowing, putting Wall Street in the lead again after a lopsided U.S.-EU trade deal revived concerns about the economic outlook and the health of corporate earnings.

US stocks were mixed Monday and the S&P 500 eked out a record high for the sixth day in a row as investors digested the announcement of a trade deal between Washington and Brussels.

Wall Street’s record-breaking, weeklong run ran out of momentum on Tuesday. The S&P 500 slipped 0.3% for its first drop after closing at an all-time high in six successive days. The Dow Jones Industrial Average sank 204 points, or 0.5%, and the Nasdaq composite shaved 0.4% off its own record.