and signs characteristic of frontotemporal lobar degeneration. Neurological skill resides in the ability to elicit symptoms and assess the validity of signs that confirm neurodegenerative and ...

The classification of frontotemporal lobar dementias ... that include prominent apraxia (corticobasal degeneration), parkinsonism (frontotemporal lobar degeneration with MAPT (microtubule ...

Limbic-predominant age-related TDP-43 encephalopathy (LATE) is a recently characterized form of dementia that is distinct ...

A new study led by Western researchers found frequent treatment with intranasal oxytocin – a hormone in the brain associated ...

Data pertaining to the pathophysiology and genetics of frontotemporal dementia primarily come from studies conducted in North America and Western Europe. More patients from underrepresented groups ...

Presa, Bailey et al. assess the feasibility and efficacy of intrathecal administration of AAV9-SUMF1 gene therapy in the Sumf1-KO mouse model of Multiple Sulfatase Deficiency. They show that it ...

A multi-task learning framework, DEMENTIA, has been developed by Prof. Li Hai and his team at the Hefei Institutes of Physical Science of the Chinese Academy of Sciences, to improve the early ...

Motor neuron disease usually refers to amyotrophic lateral sclerosis, but it can also refer to other kind of neurodegenerative disease that affect the motor neurons, such as progressive primary ...

For example, the severity of hand muscle atrophy is determined by the remaining number of motor neurons in the lateral nuclear group of the spinal anterior horn innervating the hand muscle after ...

Figure 3 sets out an approach to the assessment of cerebral atrophy. Atrophy with a focal lobar predominance is a useful starting point to help narrow the differential diagnosis in patients with ...