The final week of the year features an eclectic group of games, including five divisional contests, five favorites of at least six points, and one matchup of rookie quarterbacks. No. 2 pick Jayden Daniels and the Commanders are favored by 3.

The 49ers have nothing to play for other than pride at this point. They're facing a Lions team that has the best record in the NFC but hasn't even clinched their division yet. Detroit will be playing with a lot on the line, meaning we can expect their very best, even in a game they should have no trouble winning.

The Detroit Lions and San Francisco 49ers will square off in a rematch of last year's NFC Championship game on Monday Night Football in Week 17 at Levi's Stadium. The Lions will be looking to improve their road record to 8-0 and overall record to 14-2.