Chronic inflammation occurs when the immune system is stuck in attack-mode, sending cell after cell to defend and repair the body for months or even years. Diseases associated with chronic ...

Researchers at UT Arlington have discovered a key enzyme, IDO1, that when blocked, helps immune cells regain their ability to properly process cholesterol—something that breaks down during ...

By shutting this “off switch,” immune cells called macrophages regain their ability to soak up cholesterol, potentially ...

Scientists at The University of Texas at Arlington have identified a new enzyme that can be "turned off" to help the body ...

Reverse micelles (RMs) with confined water pools have been applied in many fields. However, the water insolubility of RMs seriously limits the scope of their application, especially those needed to ...

Scientists at The University of Texas at Arlington have identified a new enzyme that can be "turned off" to help the body ...

Many people with IBD, an umbrella term that includes ulcerative colitis and Crohn's disease, have a reduced quality of life, ...

Scientists at The University of Texas at Arlington have identified a new enzyme that can be “turned off” to help the body ...

How do drug metabolizing enzymes such as CYP2D6 influence pharmacokinetics and drug efficiency of tamoxifen and aromatase inhibitors in adjuvant breast cancer therapy?

Some of the major enzymes responsible for these inactivation steps include UGT1A4, UGT2B7, UGT2B15 and SULT1A1.

Objectives Review of efficacy and safety of Janus kinase (JAK) inhibition in immune-mediated inflammatory diseases (IMIDs).Methods A systematic literature research (SLR) of all publications on JAK ...

The overproduction of reactive oxygen species (ROS) is central to the progression of inflammatory bowel disease (IBD), which may be the potential therapeutic target. Prussian blue (PB) nanoparticles ...