Picture in your mind a traditional “landline” telephone with a coiled cord connecting the handset to the phone. The coiled telephone cord and the DNA double helix that stores the genetic material in ...

Supercoiling and looping can transmit mechanical stress along the DNA backbone that can promote the separation of the strands of the double helix at specific distant sites, exposing the DNA bases, ...

When people think of DNA, they visualize a string-like double helix structure. In reality, the DNA double helix in cells is supercoiled and constrained into loops. This supercoiling and looping are ...

Picture in your mind a traditional "landline" telephone with a coiled cord connecting the handset to the phone. The coiled telephone cord and the DNA double helix that stores the genetic material in ...

Even living cells have their own tangled problems to solve. They involve knots that arise accidentally in DNA and that can comprise its functionality. A new study by SISSA (Scuola Internazionale ...

A cell has many ways to regulate gene expression, one of which is the structure of the genome itself; active genes have to be accessible to the cellular machinery to be expressed. The DNA in the ...

While DNA is often idealised as the "molecule of life", it is also a highly sophisticated polymer that can be used for next-generation materials. Beyond the fact that it can store information, further ...

A team of physicists working at the intersection of theory and experiment are shedding new light on the 'teamwork' of molecular motors -- called RNA polymerases (RNAPs) -- that mediate DNA ...

The double helix of DNA is one of the most iconic symbols in science. By imitating the structure of this complex genetic molecule we have found a way to make artificial muscle fibers far more powerful ...

The double helix of DNA is one of the most iconic symbols in science. By imitating the structure of this complex genetic molecule we have found a way to make artificial muscle fibres far more powerful ...