Prostate cancer (PCa) is a highly prevalent malignancy, heavily characterized by complex cellular heterogeneity and highly ...

A new study that explores gene expression during heart transplant rejection marks a step forward for precision medicine approaches to treat organ rejection.

Researchers at the Department of Women's and Children's Health have used a novel technique to map which genes are active in ...

A Vanderbilt Health and TGen team applied spatial transcriptomics to heart transplant biopsies, uncovering cellular programs linked to rejection, therapy response, and cardiac allograft vasculopathy.

Researchers have developed Fullscope-seq, a long-read spatial transcriptomics platform that maps alternative transcript isoforms within intact tissues at single-cell resolution - opening new ...

Conventional transcriptomic techniques have revealed much about gene expression at the population and single-cell level—but they overlook one crucial factor: spatial context. In musculoskeletal ...

This illustration summarizes how integrated spatial transcriptomics, single-cell transcriptomics, single-cell epigenomics, and spatial epigenomics enable multi-dimensional profiling of the tumor ...

A researcher's guide to spatial transcriptomics: how sequencing- and imaging-based methods work, and how to choose a platform ...

A new study that explores gene expression during heart transplant rejection marks a step forward for precision medicine approaches to treat organ rejection.

Biological systems are inherently three-dimensional—tissues form intricate layers, networks, and architectures where cells interact in ways that extend far beyond a flat plane. To capture the true ...