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An SGLT2 pill protected the kidneys of teenagers with type 1 diabetes in a new trial

Teenagers with type 1 diabetes now have the first randomized trial evidence that an SGLT2 inhibitor can protect their kidneys ...
Medscape

Diabetic Ketoacidosis With SGLT2 Inhibitors Is Manageable

The euglycemic diabetic ketoacidosis (DKA) that has recently been associated with the use of sodium–glucose cotransporter 2 (SGLT2) inhibitors will probably turn out to be very infrequent in patients ...
Medscape

SGLT2 Inhibitor-Linked Diabetic Ketoacidosis Is Rare, but Severe

Many cases of sodium-glucose cotransporter-2 (SGLT2) inhibitor-associated diabetic ketoacidosis (DKA) are preventable, new research suggests. But physicians and patients are missing the signs and ...
The American Journal of Managed Care

FDA Warns That SGLT2 Inhibitors May Result in Ketoacidosis

The FDA said it had received 20 reports in the 15 months since the first of the SGLT2 inhibitor class was approved, and had continued to receive reports since that time. All drugs in the class were ...
MedPage Today

Is SGLT2 Inhibitor-Associated Ketoacidosis Treated With Enough Insulin?

Patients with SGLT2 inhibitor-associated diabetic ketoacidosis (DKA) received significantly lower doses of insulin in the first 24 hours of treatment compared with patients with type 1 diabetes DKA, ...
The American Journal of Managed Care

Report Compiles Data on Diabetic Ketoacidosis With SGLT2 Inhibitors

While rare, diabetic ketoacidosis occurs overwhelmingly in patients taking SGLT2 inhibitors with type 2 diabetes, according to the analysis from 3 North Carolina medical schools. A data analysis in ...
TCTMD

Higher Rates of Amputation and Ketoacidosis With SGLT2 Inhibitors: European Registry Data

(UPDATED) The use of sodium-glucose co-transporter 2 (SGLT2) inhibitors for the treatment of type 2 diabetes is associated with more than a twofold increased risk of lower-limb amputations, as well as ...
Healio

AACE/ACE position statement: DKA risk no greater with SGLT2 inhibitors

Please provide your email address to receive an email when new articles are posted on . The incidence of diabetic ketoacidosis in patients with type 2 diabetes taking an SGLT2 inhibitor is no greater ...
Nature

Euglycemic Diabetic Ketoacidosis Associated with SGLT2 Inhibitors

Euglycemic diabetic ketoacidosis (EDKA) is characterised by the triad of metabolic acidosis with elevated anion gap, ketonaemia or ketonuria and near-normal blood glucose levels, typically below 200 ...
Healio

SGLT2 inhibitor therapies may raise risk for amputation, diabetic ketoacidosis in diabetes with CVD

Please provide your email address to receive an email when new articles are posted on . MUNICH — Adults with type 2 diabetes and established CVD prescribed SGLT2 inhibitor therapy have a twofold ...
MedPage Today

Study Questions Need to Hold SGLT2 Inhibitors Before Surgery

Use of SGLT2 inhibitors before emergency surgery was not associated with an increased risk for postoperative diabetic ketoacidosis. The FDA previously issued guidance on withholding SGLT2 inhibitors ...