The development of novel therapeutics offers great hope for the fight against widespread diseases such as cancer, but they can impair the cardiovascular system, so development often fails early on.

The innermost layer of blood vessels is formed by endothelial cells, which in turn play a role in the development of diseases of the cardiovascular system. Human endothelial cells are therefore ...

Cardiovascular disease remains a leading global health burden, yet many preclinical systems still struggle to predict how candidate drugs will perform in the human heart. Rodent models are limited by ...

Two whole adult human hearts, one healthy and one diseased, have been imaged in unprecedented detail by researchers from UCL and the European Synchrotron Radiation Facility (ESRF), providing an ...