Hospital-acquired hyponatremia can be lethal. There have been multiple reports of death or permanent neurological impairment in both children and adults. The main factor contributing to the ...

Term neonates, children and young people are not given hypotonic fluids or glucose-containing fluids for intravenous (IV) fluid resuscitation. There are safety concerns about the use of hypotonic IV ...

Hypotonic fluid administration has been the standard of care for maintenance fluid therapy in acutely ill children, but this approach is associated with hospital-acquired hyponatraemia and ...

Normally, your body is made of about 50%-60% fluid, including water, blood, and lymphatic fluid. When your fluid levels are out of balance (too high or too low), serious health problems can happen.

In general, 0.25% saline is rarely used as a hydration fluid by itself. Because of the tonicity gradient, free water would enter the red blood cells, causing them to swell. This could lead to cell ...

In a new evidence-based clinical guideline, the American Academy of Pediatrics (AAP) recommends isotonic intravenous fluids (IVFs) with appropriate potassium chloride and dextrose for most children ...

(HealthDay News) – For children requiring maintenance intravenous (IV) fluids, isotonic fluids are safer than hypotonic fluids in terms of plasma sodium (pNa) levels, according to a meta-analysis ...

Term neonates, children and young people receiving intravenous (IV) fluids for routine maintenance are not given hypotonic fluids as the initial fluid. There are safety concerns about the use of ...