Azitra, Inc. (NYSE American: AZTR), a clinical stage biopharmaceutical company focused on developing innovative therapies for ...

Filaggrin is encoded by FLG, a highly unusual gene found within a cluster of more than 60 genes involved in epithelial differentiation (the epidermal differentiation complex, EDC). Uniquely, most of ...

To analyze the function of filaggrin-2 and understand the effect of its deficiency in AD in an immunological cell-free context, we downregulated its expression with shRNA technology in reconstructed ...

Eczema is a condition which causes skin inflammation. A recent evidence suggests that a deficiency in the skin’s barrier is the key to trigger eczema. The team at Newcastle University, in ...

A gene mutation and cat exposure at birth may increase a child's risk of developing eczema during their first year according to a study in PLoS Medicine. Researchers studied the association between ...

Please provide your email address to receive an email when new articles are posted on . Filaggrin expression, a marker of skin barrier function, predicts asthma in school-age children. This marker had ...

(HealthDay)—Both atopic dermatitis (AD) and loss-of-function mutations in the filaggrin gene (FLG) are independently associated with an increased risk of developing chronic irritant contact dermatitis ...

Blood samples were obtained with informed consent from 15 families with ichthyosis vulgaris and from normal ethnically matched controls. Experiments comply with all principles of the Helsinki Accord.

Knowledge of the existence of filaggrin (FLG) gene mutations might be helpful for a subclassification of patients with atopic dermatitis (AD) which can be used to introduce individualized treatments.

Scientists have uncovered evidence that a deficiency in the skin's barrier is key to triggering eczema. The team at Newcastle University, in collaboration with scientists at Stiefel, a GSK company, ...

Eczema is a genetic disorder with an environmental trigger, which affects one in three people at some time in their life. People with eczema essentially have sensitive skin that is easily irritated.