In my previous post, I suggested that regular cannabis use gradually shifts the brain into a new adaptive operating state—one ...

Does using alcohol, nicotine, or cannabis engender addiction by changing the structure of brains, or does the structure of brains incline some people toward using those substances? In standard brain ...

Researchers at Kanazawa University identified dopamine-driven neural mechanisms of motivation in a mouse model of behavioral addiction, offering insights into treatment. Assistant Professor Naoya ...

Remarkable scientific progress over the past five decades has helped us develop knowledge of how drugs of abuse induce pleasure, reinforce use, and lead to the compulsive self-administration we call ...

Using animal models representing isolated features of the disease, the team discovered that alcohol dramatically reduces ...

Addiction is one of the most common and consequential chronic medical conditions in the United States. Nationwide, more than 46 million people met the criteria for a substance abuse disorder as of ...