The 49ers' defense let them down as they gave up 242 yards and four touchdowns through the air to Cardinals star Kyler Murray ...

The Detroit Lions had three players fined following their Week 17 game against the San Francisco 49ers.

Jared Goff threw three touchdown passes and the Detroit Lions tuned up for their Week 18 division showdown against Minnesota ...

We knew most of the postseason bracket entering Sunday Night Football. But the Minnesota Vikings-Detroit Lions matchup ...

Newsweek Sports' expert predictions for Detroit Lions vs. San Francisco 49ers on Monday Night Football Week 17.

The Lions have just under 20 players on injured reserve, including starters like defensive end Aidan Hutchinson, defensive ...

And don't be surprised if the Lions-Vikings winner-take-all finale smashes the Sunday Night Football high mark for this year, ...

The Detroit Lions had 10 quarterback hits and held Minnesota QB Sam Darnold to 18-for-41 passing for 166 yards and no touchdowns on Sunday.

Detroit Lions defensive back Kerby Joseph vowed to have his teammates' backs after getting into a scuffle with San Francisco ...

The Detroit Lions have a short week to prepare for a pivotal matchup against Minnesota, and they will not complain about that ...

The Detroit Lions finally got revenge on the San Francisco 49ers on a day that Dan Campbell decided to play his starters to ...

Detroit improved to 14-2 and will carry momentum into next week's critical game against Minnesota for the NFC's top seed.