The No. 11 USC Trojans will travel to face the No. 18 Michigan Wolverines. This is a big game for the USC offense, led by Trojans quarterback Miller Moss as he looks to pick up the win in Ann Arbor.

It’s fitting that USC’s debut in its new league comes against Michigan, the Big Ten standard-bearer for the past three seasons. The Wolverines embodied old-school Big Ten physicality while winning three consecutive conference championships and the 2023 national championship.

There are dozens of interesting subplots and nuances to apply to USC versus Michigan, but five keys stand out above the others for the Trojans.