Gut microbiome alterations in high-fat-diet-fed mice are ... - Nature
WEBMay 20, 2021 · Here, we evaluated the efficacy of multiple clinically relevant bactericidal antibiotics in HFD-fed mice infected with methicillin-resistant Staphylococcus aureus (MRSA) or Escherichia coli.
C57BL/6J substrain differences in response to high-fat diet ...
WEBAug 20, 2020 · On HFD all three groups of mice showed increased percentage of fat compared to chow, in agreement with the similar increased weight gain as a result of HFD (Suppl. Fig. 3a–c).
Insights from a high-fat diet fed mouse model with a humanized …
WEBMay 9, 2022 · Upon feeding a high-fat or matched ingredient control diet for 12 weeks, cDNA-uPA/SCID chimeric mice developed extensive macrovesicular steatosis, a feature previously associated with reduced growth hormone action. However, mice were resistant to diet-induced obesity and remained glucose tolerant.
High-fat diet promotes renal injury by inducing oxidative stress …
WEBOct 24, 2020 · Here, we investigated the mechanism whereby long-term high-fat diet (HFD) feeding induces renal injury in mice. The C57BL/6 mice fed HFD for 16 weeks developed obesity, diabetes, and kidney...
Lonicerin attenuates high-fat diet-induced hepatic steatosis …
WEB2 days ago · Oil red O staining further confirmed substantial lipid deposition in HFD-fed mice, as evidenced by the abundance of red droplets (Fig. 1 B). Lonicerin intervention significantly reduced liver size, as well as the number and size of fat droplets in the liver of HFD-fed mice, showing a lipid-lowering efficacy comparable to the positive control.
High-fat diet-induced adipose tissue expansion occurs prior to …
WEBSep 1, 2020 · A detailed time course in HFD-fed mice was investigated by evaluating the initiation of glucose homeostasis impairment, dyslipidemia, systemic insulin sensitivity, monocyte chemoattractant protein-1 (MCP-1) levels, epididymal white adipose tissue (eWAT) expansion, macrophage content changes, pro-inflammatory (M1)/anti-inflammatory (M2) macrophag...
Exercise in mice ameliorates high-fat diet-induced nonalcoholic …
WEBMar 3, 2021 · This study investigates the mechanisms by which exercise suppresses NAFLD development induced by a high-fat diet (HFD) in mice. Male 6-week-old C57BL/6J mice were fed a normal diet or HFD for 12 weeks and then induced to swim or remain sedentary for 8 weeks.
FBXO28 reduces high-fat diet-induced hyperlipidemia in mice by ...
WEBMay 2, 2024 · Mice were fed with high-fat diet (HFD) to elicit obesity, and 3T3-L1 preadipocytes were stimulated with MDI cocktail (IBMX, DEX and insulin) to evoke differentiation.
High fat diet induced obesity model using four strains of mice: …
WEBMar 19, 2020 · Liver and fat index of mice fed with normal chow (CON) and HFD (MOD) of four mouse strains: Kunming, C57BL/6, BALB/c and ICR. Different superscript letters among bars denote significant difference (P<0.05) according to Tukey’s test.
Amoxicillin modulates gut microbiota to improve short-term high …
WEBOct 13, 2022 · The short course of amoxicillin treatment to HFD-fed mice resulted in beneficial effects by significantly reducing fasting blood glucose and skewing the number of thrombocytes towards a normal range. Remarkably, we observed a significant remodelling of gut microbiota in amoxicillin-treated HFD-fed mice.
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